Macular and submacular choroidal microvasculature in patients with primary open-angle glaucoma and high myopia
| Autor: | Fengbin Lin, Zhen Qiu, Fei Li, Yu Chen, Yuying Peng, Meiling Chen, Yunhe Song, Jian Xiong, Weijing Cheng, Yuhong Liu, Mingkui Tan, Xiulan Zhang, Robert Weinreb |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | British Journal of Ophthalmology. 107:650-656 |
| ISSN: | 1468-2079 0007-1161 |
| DOI: | 10.1136/bjophthalmol-2021-319557 |
| Popis: | AimsTo characterise the influence of primary open-angle glaucoma (POAG) and high myopia (HM) on the macular and choroidal capillary density (CD).MethodsTwo hundred and seven eyes were enrolled, including 80 POAG without HM, 50 POAG with HM, 31 HM without POAG and 46 normal controls. A fovea-centred 6×6 mm optical coherence tomography angiography scan was performed to obtain the CD of the superficial capillary plexus (SCP), deep capillary plexus (DCP) and choriocapillaris. Macular and choroidal CDs were compared among the groups and the association of CDs with visual field mean deviation (MD) was determined using linear regression models.ResultsCompared with normal eyes, SCP CD was decreased in the POAG without HM group (pConclusionsPOAG and HM reduced macular CD in different layers of the retinal capillary plexus and both particularly in the outer ring of the 6×6 mm scans. Furthermore, assessment of the CD in the outer ring of the SCP may facilitate the diagnosis of glaucoma in eyes with HM. |
| Databáze: | OpenAIRE |
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