Diagnosis and treatment of prosthetic aortic graft infections: confusion and inconsistency in the absence of evidence or consensus
| Autor: | Hilary Humphreys, C. Kelly, S. F. FitzGerald |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Prosthesis-Related Infections medicine.drug_class Definitive Therapy medicine.medical_treatment Antibiotics Prosthesis medicine Humans Pharmacology (medical) Intensive care medicine Aorta Antibacterial agent Confusion Pharmacology Aortic graft Cross Infection business.industry Antimicrobial medicine.disease Surgery Anti-Bacterial Agents Blood Vessel Prosthesis Infectious Diseases Infective endocarditis medicine.symptom business |
| Zdroj: | The Journal of antimicrobial chemotherapy. 56(6) |
| ISSN: | 0305-7453 |
| Popis: | Prosthetic aortic graft infections represent a major diagnostic and therapeutic challenge. Although a combination of clinical assessment, imaging and microbiological investigations is usually helpful, there are no agreed criteria to confirm a diagnosis. Potential pathogens isolated from superficial specimens may be misleading but influence the choice of antimicrobial agents. Removal of the infected material is strongly recommended. However, this is not always possible in the very debilitated or clinically unstable patient. The choice of which antimicrobial agents to administer as empirical or definitive therapy and the duration of treatment are unclear. A multi-disciplinary group is required to offer guidance, based on what evidence there is, and to provide expert consensus (as is the case for infective endocarditis) to optimize the management of these difficult infections. |
| Databáze: | OpenAIRE |
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