Long-lasting Consequences of Early Life Stress on Brain Structure, Emotion and Cognition

Autor: Krugers, H., Joëls, M., Pariante, C.M., Lapiz-Bluhm, M.D.
Přispěvatelé: Structural and Functional Plasticity of the nervous system (SILS, FNWI)
Rok vydání: 2014
Předmět:
Zdroj: Behavioral Neurobiology of Stress-related Disorders ISBN: 9783662451250
Behavioral neurobiology of stress-related disorders, 81-92
STARTPAGE=81;ENDPAGE=92;TITLE=Behavioral neurobiology of stress-related disorders
DOI: 10.1007/7854_2014_289
Popis: During the perinatal period, the brain undergoes substantial structural changes, synaptic rearrangements, and development of neuronal circuits which ultimately determine brain function and behavior. Environmental factors-such as exposure to adverse experiences-have major impact on brain function and structure during this sensitive period. These alterations can be long-lasting, and have been implicated in psychopathology such as cognitive decline and emotional dysfunction. Here we briefly review how early postnatal adversity determines structure and function of the hippocampus, amygdala, and prefrontal cortex (PFC) areas, which are crucial for proper cognitive and emotional function.
Databáze: OpenAIRE