Ischemic Heart Disease in Monozygotic Twins
| Autor: | Albert H. Douglas |
|---|---|
| Rok vydání: | 1966 |
| Předmět: |
Adult
Male medicine.medical_specialty Hypercholesterolemia Coronary Disease Disease Coronary disease Electrocardiography Internal medicine Diabetes mellitus Diseases in Twins medicine Humans Aged business.industry Clinical course Atrial fibrillation General Medicine medicine.disease United States Europe Young age Cardiology Age of onset Ischemic heart business |
| Zdroj: | Diseases of the Chest. 49:522-528 |
| ISSN: | 0096-0217 |
| DOI: | 10.1378/chest.49.5.522 |
| Popis: | SUMMARY Three sets of monozygotic twins with proved ischemic heart disease are reported. All were men. Hypercholesterolemia was observed in the five instances in which determinations were available. Two of the three fathers died of heart attacks. The age of onset of ischemic heart disease was similar and within a three year range for two of the sets, and in the third set coronary disease appeared at a relatively young age in both twins. The clinical course was significantly different in brothers with the same genetic background, demonstrating the importance of environmental factors. In one set, diabetes mellitus and atrial fibrillation were discovered at about the same age. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|