Numerical simulation of the influence of a left ventricular assist device on the cardiovascular system
| Autor: | Paul K. Blanksma, D Mihaylov, Gerhard Rakhorst, Gijsbertus Jacob Verkerke, A.A. Geertsema |
|---|---|
| Přispěvatelé: | Extremities Pain and Disability (EXPAND) |
| Jazyk: | angličtina |
| Rok vydání: | 2000 |
| Předmět: |
medicine.medical_specialty
LVAD left ventricle medicine.medical_treatment 030232 urology & nephrology Biomedical Engineering Diastole Pulsatile flow Medicine (miscellaneous) Bioengineering 030204 cardiovascular system & hematology mechanical circulatory support system PUCA-PUMP Biomaterials 03 medical and health sciences 0302 clinical medicine medicine.artery Internal medicine Ascending aorta medicine business.industry General Medicine Catheter medicine.anatomical_structure Ventricle Ventricular assist device Circulatory system Cardiology cardiovascular system business numerical model CATHETER PUMP Artery |
| Zdroj: | International journal of artificial organs, 23(11), 765-773. Wichtig Editore s.r.l. |
| ISSN: | 0391-3988 |
| Popis: | The PUCA (pulsatile catheter) pump is a left ventricular assist device (LVAD) capable of unloading the left ventricle (LV) and improving coronary flow by providing a counterpulsation effect. It consists of an extracorporeal located membrane pump, coupled to a transarterial catheter that enters the body via a superficial artery and ends in the LV. Blood is aspirated from the LV and pumped in the ascending aorta through the same catheter guided by a valve system. Timing and frequency of the PUCA pump influence its efficacy. To study the influence of several pump parameters a numerical model of the device and the circulatory system has been developed. Results of animal experiments were used to validate the model. Optimization studies resulted in a pump configuration with a stroke volume of 50 cc and pump:heart frequency mode of 1:2 that starts ejection at the beginning of diastole. |
| Databáze: | OpenAIRE |
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