Effects of Mannitol and Iohexol Infusions on the Renal Cortical Blood Flow in Dehydrated Mice

Autor: S.-O. Hietala, Barry Högström, P. Rooth
Rok vydání: 1996
Předmět:
Zdroj: Acta Radiologica. 37:591-595
ISSN: 1600-0455
0284-1851
DOI: 10.1177/02841851960373p233
Popis: In vivo fluorescence microscopy was used in experimental studies of renal cortical microcirculation in mice. The effects of intravenous infusions of equimolar concentrations of mannitol and iohexol were studied in normal lean mice and obese/hyperglycemic mice after dehydration overnight. All infusions produced marked effects in distribution and velocity of renal cortical blood flow. Initially increased blood flow was seen in a number of capillaries after infusion of both mannitol and iohexol, and renal cortical blood flow was inhomogeneous for different capillaries. A significantly (p
Databáze: OpenAIRE