Effects of Mannitol and Iohexol Infusions on the Renal Cortical Blood Flow in Dehydrated Mice
Autor: | S.-O. Hietala, Barry Högström, P. Rooth |
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Rok vydání: | 1996 |
Předmět: |
medicine.medical_specialty
Pathology Kidney Cortex Iohexol Renal cortex Contrast Media Mice Obese Renal Circulation 030218 nuclear medicine & medical imaging Microcirculation Nephropathy Mice 03 medical and health sciences 0302 clinical medicine In vivo Internal medicine medicine Animals Mannitol Radiology Nuclear Medicine and imaging Dehydration Radiological and Ultrasound Technology business.industry General Medicine Blood flow medicine.disease Contrast medium Endocrinology medicine.anatomical_structure Microscopy Fluorescence Hyperglycemia 030220 oncology & carcinogenesis Female business medicine.drug |
Zdroj: | Acta Radiologica. 37:591-595 |
ISSN: | 1600-0455 0284-1851 |
DOI: | 10.1177/02841851960373p233 |
Popis: | In vivo fluorescence microscopy was used in experimental studies of renal cortical microcirculation in mice. The effects of intravenous infusions of equimolar concentrations of mannitol and iohexol were studied in normal lean mice and obese/hyperglycemic mice after dehydration overnight. All infusions produced marked effects in distribution and velocity of renal cortical blood flow. Initially increased blood flow was seen in a number of capillaries after infusion of both mannitol and iohexol, and renal cortical blood flow was inhomogeneous for different capillaries. A significantly (p |
Databáze: | OpenAIRE |
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