Interpretation of plasma brain natriuretic peptide concentrations may require adjustment for patient's age
| Autor: | Jennifer C Cooke, Mark J. Monaghan, Thuraia Nageh, Roy Sherwood, Noreen Meehan, D.T. Chin |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Male Myocardial ischaemia medicine.medical_specialty Heart disease medicine.drug_class Clinical Biochemistry Population Myocardial Infarction Ventricular Function Left Internal medicine Natriuretic Peptide Brain medicine Natriuretic peptide Humans cardiovascular diseases Myocardial infarction education Aged Aged 80 and over Heart Failure education.field_of_study Ventricular function business.industry Age Factors General Medicine Middle Aged medicine.disease Brain natriuretic peptide Prognosis Endocrinology Heart failure Cardiology Female business Echocardiography Stress |
| Zdroj: | Annals of clinical biochemistry. 39(Pt 2) |
| ISSN: | 0004-5632 |
| Popis: | Background: Brain natriuretic peptide (BNP) is increasingly recognized as a practical, reliable and accurate indicator of left ventricular function and may have an important prognostic role in determining outcome following myocardial infarction and heart failure. Methods and Results: We studied a total of 60 patients referred for dobutamine-stress echocardiography to evaluate possible reversible myocardial ischaemia. There was no echocardiographic evidence of structural or functional heart disease in any of the patients included in the study. Blood was sampled for BNP at rest, prior to dobutamine-stress. We found a significant linear correlation between BNP concentrations and patients' age, in the absence of structural or functional heart disease ( rs=0.53, 95%CI 0.25-0.73, P |
| Databáze: | OpenAIRE |
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