Genetic study of motor functions in Drosophila melanogaster

Autor: Julia V Bragina, Nataliya G Besedina, Sergey A Fedotov, Elena A Kamysheva, Larisa V Danilenkova, Nikolay G Kamyshev
Rok vydání: 2012
Předmět:
Zdroj: Экологическая генетика, Vol 10, Iss 1, Pp 51-61 (2012)
ISSN: 2411-9202
1811-0932
DOI: 10.17816/ecogen10151-61
Popis: To investigate molecular mechanisms of central pattern generators (CPG s) functioning, we carried out a screening of collection of Drosophila P-insertional mutants for strong deviations in locomotion and courtship song. In 21 mutants, the site of the P-insertion was localized by sequencing of the fragments of genomic DNA flanking the P-element. Bioinformational analysis revealed a list of candidate genes, potential players in development and functioning of CPG s. Possible involvement of certain identified genes in rhythmic motor activity is suggested for the first time (CG15630, Map205).
Databáze: OpenAIRE