Genetic study of motor functions in Drosophila melanogaster
Autor: | Julia V Bragina, Nataliya G Besedina, Sergey A Fedotov, Elena A Kamysheva, Larisa V Danilenkova, Nikolay G Kamyshev |
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Rok vydání: | 2012 |
Předmět: |
Candidate gene
p-элемент lcsh:QH426-470 media_common.quotation_subject Mutant локомоция моторные функции инсерционные мутации Biochemistry Courtship chemistry.chemical_compound Genetics Motor activity звукопродукция Drosophila (subgenus) Genetics (clinical) Ecology Evolution Behavior and Systematics песня ухаживания media_common гены-кандидаты Ecology biology biology.organism_classification дрозофила lcsh:Genetics CpG site chemistry скрининг Drosophila melanogaster DNA |
Zdroj: | Экологическая генетика, Vol 10, Iss 1, Pp 51-61 (2012) |
ISSN: | 2411-9202 1811-0932 |
DOI: | 10.17816/ecogen10151-61 |
Popis: | To investigate molecular mechanisms of central pattern generators (CPG s) functioning, we carried out a screening of collection of Drosophila P-insertional mutants for strong deviations in locomotion and courtship song. In 21 mutants, the site of the P-insertion was localized by sequencing of the fragments of genomic DNA flanking the P-element. Bioinformational analysis revealed a list of candidate genes, potential players in development and functioning of CPG s. Possible involvement of certain identified genes in rhythmic motor activity is suggested for the first time (CG15630, Map205). |
Databáze: | OpenAIRE |
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