Depression and its association with peritonitis in long-term peritoneal dialysis patients
| Autor: | Nancy Gorban-Brennan, Fredric O Finkelstein, Diane Wuerth, Alan S. Kliger, Suzanne Watnick, Laura Troidle |
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| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Peritonitis Coronary Disease Comorbidity Severity of Illness Index Peritoneal dialysis Recurrence Risk Factors Internal medicine Diabetes Mellitus medicine Humans Prospective Studies Prospective cohort study Gram-Positive Bacterial Infections Depression (differential diagnoses) Aged Proportional Hazards Models Psychological Tests Depression business.industry Hazard ratio Beck Depression Inventory Middle Aged medicine.disease Surgery Nephrology Kidney Failure Chronic Female Hemodialysis Gram-Negative Bacterial Infections business Peritoneal Dialysis |
| Zdroj: | American Journal of Kidney Diseases. 42:350-354 |
| ISSN: | 0272-6386 |
| DOI: | 10.1016/s0272-6386(03)00661-9 |
| Popis: | Depression is the most common psychological disorder among patients with end-stage renal disease and has been associated with mortality in patients maintained on hemodialysis therapy. Peritonitis is the leading cause of technique failure among long-term peritoneal dialysis (PD) patients. This prospective study is designed to examine the relationship between depression and peritonitis.All patients on long-term PD therapy in our unit between January 1, 1997, and January 31, 2002, completed a Beck Depression Inventory (BDI) assessment at 6-month intervals. BDI scores were analyzed 2 ways. First, patients were placed into either group I (BDI score10) or group II (BDI scoreor = 11) and were reclassified based on subsequent scores. Second, multivariable analysis was performed looking at initial BDI score as a risk factor for peritonitis, adjusting for age older than 65 years, diabetes, coronary artery disease, and race.One hundred sixty-two patients were enrolled, and 281 individual BDI assessments were completed. There was a significantly greater incidence of diabetes and coronary artery disease in group II. Rates for overall and gram-positive peritonitis were significantly greater in group II patients compared with group I patients. Using Cox regression, only BDI score of 11 or greater was associated with the development of peritonitis (hazard ratio, 2.7; 95% confidence interval, 1.2 to 6.0).There is an association between BDI score of 11 or greater and the development of peritonitis. Whether treatment of depression can impact on the rate of peritonitis remains to be examined. |
| Databáze: | OpenAIRE |
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