Long-term efficacy of hepatitis B vaccination in healthcare workers of Oil Company Hospital, Tehran, Iran (1989–2005)
| Autor: | Mirmohsen Sharifi Bonab, Seyed Mohammad Miri, Seyed Moayed Alavian, Siavash Mansouri, Shervin Assari, Mehdi Abouzari |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty HBsAg Infectious Disease Transmission Patient-to-Professional medicine.disease_cause Sex Factors Orthohepadnavirus Internal medicine medicine Humans Hepatitis B Vaccines Hepatitis B Antibodies Hepatitis Hepatitis B virus Hepatitis B Surface Antigens Hepatology biology business.industry Vaccination Gastroenterology Middle Aged Hepatitis B biology.organism_classification medicine.disease Hepatitis B Core Antigens Personnel Hospital Titer Hepadnaviridae Immunology Female Viral disease business Follow-Up Studies |
| Zdroj: | European Journal of Gastroenterology & Hepatology. 20:131-134 |
| ISSN: | 0954-691X |
| DOI: | 10.1097/meg.0b013e3282f1cc28 |
| Popis: | OBJECTIVE This study was conducted to evaluate the 16-year efficacy of hepatitis B virus (HBV) vaccine in healthcare workers of Oil Company Hospital, Tehran, Iran. METHODS Two hundred healthcare workers were enrolled in the study in 1989. All HBV markers were tested and those with positive HBV markers, positive antihepatitis C virus or anti-HIV were excluded from the study. The remaining participants received three doses of HBV vaccine and again all of our participants were reevaluated in 2005. Hepatitis B surface antigen (HBsAg), antihepatitis B surface antibody (anti-HBsAb), and antihepatitis B core antibody (anti-HBcAb) were checked in all participants and those with anti-HBcAb above 10 IU/l were excluded from the final evaluation. RESULTS No participant was positive for HBsAg in either 1989 or 2005. Protective levels of anti-HBsAb were absent in all participants in 1989, but present in 67 (80.7%) participants in 2005 (P |
| Databáze: | OpenAIRE |
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