Graft Survival After Cardiac Transplantation for Alcohol Cardiomyopathy
| Autor: | D. Marshall Brinkley, Eric Novak, Edward M. Geltman, Veli K. Topkara |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Cardiomyopathy Dilated Male medicine.medical_specialty medicine.medical_treatment Cardiomyopathy Internal medicine Idiopathic dilated cardiomyopathy medicine Humans Aged Proportional Hazards Models Cause of death Heart transplantation Transplantation business.industry Proportional hazards model Graft Survival Dilated cardiomyopathy Middle Aged medicine.disease Alcoholism Cohort Cardiology Heart Transplantation Female business |
| Zdroj: | Transplantation. 98:465-469 |
| ISSN: | 0041-1337 |
| DOI: | 10.1097/tp.0000000000000083 |
| Popis: | BACKGROUND Alcohol cardiomyopathy (ACM) constitutes up to 40% of patients with non-ischemic dilated cardiomyopathy. Transplant-free survival is worse for patients with ACM versus idiopathic dilated cardiomyopathy (IDCM) with continued exposure. The prognosis for patients with ACM after cardiac transplantation is unknown. METHODS We evaluated adults who underwent single-organ, cardiac transplantation from 1994 to 2009 with a diagnosis of ACM (n=134) or IDCM (n=10,243) in the Organ Procurement Transplantation Network registry. Kaplan-Meier curves were generated by cohort for time until graft failure, cardiac allograft vasculopathy, and hospitalization for rejection. A Cox proportional hazards model was created to determine factors associated with each outcome. RESULTS Patients with ACM were more likely to be males (P |
| Databáze: | OpenAIRE |
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