Neurohormonal Activation and Left Atrium Remodeling in Mitral Stenosis
Autor: | Nani Hersunarti, Vidya Gilang Rejeki, Bambang Budi Siswanto |
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Rok vydání: | 2017 |
Předmět: |
lcsh:Diseases of the circulatory (Cardiovascular) system
medicine.medical_specialty business.industry Left Atrial Neurohormonal activation Left Atrial Remodeling Left atrium Mitral Stenosis medicine.disease Stenosis medicine.anatomical_structure lcsh:RC666-701 Internal medicine cardiovascular system medicine Cardiology cardiovascular diseases business |
Zdroj: | Majalah Kardiologi Indonesia, Vol 37, Iss 1 (2017) |
ISSN: | 2620-4762 0126-3773 |
DOI: | 10.30701/ijc.v37i1.555 |
Popis: | Mitral stenosis is closely related with the hemodynamic consequences of obstructed mitral leaflet. Definitive therapy in mitral stenosis is mechanical intervention. Late presentation of mitral stenosis patients to medical facilities due to limited health facilities and Indonesians demographic, often make patients condition deteriorates, in which intervention need to be delayed or even no longer suitable. Stretched left atrium and reduced cardiac output stimulate several neurohormonal activation; renin-angiotensin-aldosterone and symphatetic nervous system. Left atrial remodeling further worsen hemodynamic ststus. Renin-angiotensin-aldosterone and sympathetic blockage could improve mitral stenosis patients condition with close observation to hypotension status. |
Databáze: | OpenAIRE |
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