High-resolution and sensitivity bi-directional x-ray phase contrast imaging using 2D Talbot array illuminators

Autor: Christian Petrich, Pierre Thibault, Alex Gustschin, Jörg U. Hammel, Madleen Busse, Julia Herzen, Mirko Riedel, Wolfgang Noichl, Wolfgang Gottwald, Sheila E. Francis, Julian Moosmann, Felix Beckmann, Kirsten Taphorn
Přispěvatelé: Gustschin, Alex, Riedel, Mirko, Taphorn, Kirsten, Petrich, Christian, Gottwald, Wolfgang, Noichl, Wolfgang, Busse, Madleen, Francis, Sheila E., Beckmann, Felix, Hammel, J??rg U., Moosmann, Julian, Thibault, Pierre, Herzen, Julia
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Gustschin, A.; Riedel, M.; Taphorn, K.; Petrich, C.; Gottwald, W.; Noichl, W.; Busse, M.; Francis, S.; Beckmann, F.; Hammel, J.; Moosmann, J.; Thibault, P.; Herzen, J.: High-resolution and sensitivity bi-directional x-ray phase contrast imaging using 2D Talbot array illuminators. In: Optica. Vol. 8 (2021) 12, 1588-1595. (DOI: /10.1364/optica.441004)
Optica 8(12), 1588-1595 (2021). doi:10.1364/OPTICA.441004
Optica
ISSN: 2334-2536
DOI: 10.1364/optica.441004)
Popis: Optica 8(12), 1588 - 1595 (2021). doi:10.1364/OPTICA.441004
Two-dimensional (2D) Talbot array illuminators (TAIs) were designed, fabricated, and evaluated for high-resolution high-contrast x-ray phase imaging of soft tissue at 10���20 keV. The TAIs create intensity modulations with a high compression ratio on the micrometer scale at short propagation distances. Their performance was compared with various other wavefront markers in terms of period, visibility, flux efficiency, and flexibility to be adapted for limited beam coherence and detector resolution. Differential x-ray phase contrast and dark-field imaging were demonstrated with a one-dimensional, linear phase stepping approach yielding 2D phase sensitivity using unified modulated pattern analysis (UMPA) for phase retrieval. The method was employed for x-ray phase computed tomography reaching a resolution of 3 ��m on an unstained murine artery. It opens new possibilities for three-dimensional, non-destructive, and quantitative imaging of soft matter such as virtual histology. The phase modulators can also be used for various other x-ray applications such as dynamic phase imaging, super-resolution structured illumination microscopy, or wavefront sensing.
Published by OSA, Washington, DC
Databáze: OpenAIRE