Nutrient Malassimilation Following Total Gastrectomy
| Autor: | R. Bragelmann, B. Schneider, Reinhold W. Stockbrügger, D. Rosemeyer, W. Zilly, U. Armbrecht |
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| Přispěvatelé: | Interne Geneeskunde, RS: NUTRIM School of Nutrition and Translational Research in Metabolism |
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty Malabsorption medicine.medical_treatment Gastroenterology Excretion Postoperative Complications Malabsorption Syndromes Gastrectomy Risk Factors Stomach Neoplasms Internal medicine medicine Humans Exocrine pancreatic insufficiency Aged Chi-Square Distribution business.industry Incidence Iron deficiency Middle Aged medicine.disease Pathophysiology Malnutrition Nutrition Assessment Evaluation Studies as Topic Female business Body mass index Follow-Up Studies |
| Zdroj: | Scandinavian Journal of Gastroenterology, 31, 26-33. Informa Healthcare |
| ISSN: | 1502-7708 0036-5521 |
| Popis: | Nutrient malassimilation following total gastrectomy.Bragelmann R, Armbrecht U, Rosemeyer D, Schneider B, Zilly W, Stockbrugger RW.Dept. of Gastroenterology, Academisch Hospital Maastricht, The Netherlands.BACKGROUND: The aim of the study was to elucidate the degree and the pathophysiology of abdominal symptoms, malnutrition and malassimilation after total gastrectomy. METHODS: In 174 consecutive patients, with potentially curative total gastrectomy for gastric malignancy, subjective symptoms and objective parameters of malassimilation were evaluated. RESULTS: Abdominal symptoms were present in 86% of the patients. In spite of a high daily calorie intake (median 37.8 kcal/kg body weight) mean body mass index had been decreasing since good health. Anaemia was found in 46%, sideropenia in 31% and oesophagitis in 26%. Mean faecal fat excretion was 17.4 (1.4) g/day and mean fat malassimilation 14.8% (1.1) of the intake. A shortened small-bowel transit was measured in 21.7% of the patients, and bacterial overgrowth was present in 37.7%. CONCLUSIONS: Malassimilation post total gastrectomy seems to be multifactorial. Shortened small-bowel transit and subsequent dyssynchrony of pancreatic enzyme supply seem to be of major importance. |
| Databáze: | OpenAIRE |
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