Delayed closure of ductus arteriosus in term newborns with congenital hypothyroidism: effect of L-thyroxine therapy

Autor:	G. F. Guarnieri, N. Laforgia, A. Mautone, G. Balducci
Rok vydání:	2007
Předmět:	Male Thyroxine Echocardiography Pediatrics Perinatology and Child Health Congenital Hypothyroidism Infant Newborn Humans Thyrotropin Female Cardiology and Cardiovascular Medicine Ductus Arteriosus Patent Follow-Up Studies
Zdroj:	Pediatric cardiology. 29(2)
ISSN:	0172-0643
Popis:	Congenital hypothyroidism is associated with increased incidence of congenital defects (15.6%), frequently involving the heart (5.8%). Only few studies have evaluated the association between congenital hypothyroidism and patent ductus arteriosus. We report on two term newborns affected by thyroid agenesis and patent ductus arteriosus that closed after starting L-thyroxine substitutive therapy. This association suggests a close relation between hypothyroidism and patent ductus arteriosus. Hypothyroidism should be considered in term infants with patent ductus arteriosus because thyroid hormone production is among the prerequisites for postnatal ductal closure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2668b60d7018fa3781ee3dc62884be6d https://pubmed.ncbi.nlm.nih.gov/17676369 Zobrazit plný text záznamu Full text from SpringerLink