Importance of measuring the fractional flow reserve in patients receiving hemodialysis
| Autor: | Yoshinori Tsubakimoto, Makoto Kitamura, Akira Ueoka, Hiroshi Fujita, Masato Nishimura, Tomohiko Sakatani, Keiji Inoue, Akiko Matsuo, Yoshiaki Shimoda, Naoki Maruyama, Eigo Kishita |
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| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry medicine.medical_treatment Ischemia Mean Aortic Pressure Interventional radiology General Medicine Fractional flow reserve medicine.disease Coronary artery disease Stenosis Internal medicine Angiography medicine Cardiology Radiology Nuclear Medicine and imaging Hemodialysis Radiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Cardiovascular Intervention and Therapeutics. 26:215-221 |
| ISSN: | 1868-4297 1868-4300 |
| Popis: | Angiography is not always an accurate indicator of physiologically significant stenosis. We examined the usefulness of functional evaluation of coronary stenosis severity by determining the fractional flow reserve (FFR) using a pressure wire in patients who received hemodialysis with angiographically intermediate lesions. We recruited 44 patients with intermediate lesions; of these, 22 were undergoing hemodialysis while 22 were not. Quantitative coronary angiography (QCA) was performed to measure the minimal lumen diameter (MLD) and calculate the percent diameter stenosis (%DS). The FFR was calculated as the ratio of the coronary pressure at the distal stenotic site to the mean aortic pressure during maximum hyperemia. In each group, we investigated the relationship between the FFR and %DS and FFR and MLD. The patients in the hemodialysis group were significantly younger and had more calcified and type B2/C lesions than those in the non-dialysis group. Although the FFR was correlated with both %DS (r = 0.71, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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