To hum or not to hum: Neural transcriptome signature of male courtship vocalization in a teleost fish
Autor: | Ni Y. Feng, Andrew H. Bass, Joel A. Tripp |
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Rok vydání: | 2021 |
Předmět: |
0301 basic medicine
Regulation of gene expression biology Courtship display media_common.quotation_subject Circadian clock Midshipman fish biology.organism_classification Courtship CLOCK 03 medical and health sciences Behavioral Neuroscience 030104 developmental biology 0302 clinical medicine Neurology Porichthys notatus Genetics Circadian rhythm Neuroscience 030217 neurology & neurosurgery media_common |
Zdroj: | Genes, brain, and behaviorREFERENCES. |
ISSN: | 1601-183X |
Popis: | For many animal species, vocal communication is a critical social behavior and often a necessary component of reproductive success. Additionally, vocalizations are often demanding motor acts. Wanting to know whether a specific molecular toolkit might be required for vocalization, we used RNA-sequencing to investigate neural gene expression underlying the performance of an extreme vocal behavior, the courtship hum of the plainfin midshipman fish (Porichthys notatus). Single hums can last up to two hours and may be repeated throughout an evening of courtship activity. We asked whether vocal behavioral states are associated with specific gene expression signatures in key brain regions that regulate vocalization by comparing transcript expression levels in humming versus non-humming males. We find that the circadian-related genes period3 and Clock are significantly upregulated in the vocal motor nucleus and preoptic area-anterior hypothalamus, respectively, in humming compared to non-humming males, indicating that internal circadian clocks may differ between these divergent behavioral states. In addition, we identify suites of differentially expressed genes related to synaptic transmission, ion channels and transport, and neuropeptide and hormone signaling, and metabolism and antioxidant activity that together may support the neural and energetic demands of humming behavior. Comparisons of transcript expression across regions stress regional differences in brain gene expression, while also showing coordinated gene regulation in the vocal motor circuit in preparation for courtship behavior. These results underscore the role of differential gene expression in shifts between behavioral states, in this case neuroendocrine, motor and circadian control of courtship vocalization. |
Databáze: | OpenAIRE |
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