Significantly reducing blood loss via a peri-articular injection of tranexamic acid during total knee arthroplasty: a retrospective study
Autor: | Po Kuei Wu, Yu Kuan Lin, Chao Ming Chen, Cheng Fong Chen, Shang Wen Tsai, Wei Ming Chen, Jesse Chieh Szu Yang |
---|---|
Rok vydání: | 2021 |
Předmět: |
musculoskeletal diseases
Tranexamic acid medicine.medical_specialty Blood transfusion Deep vein medicine.medical_treatment Blood Loss Surgical Diseases of the musculoskeletal system Postoperative Hemorrhage Injections Intra-Articular Rheumatology medicine Humans Orthopedics and Sports Medicine Peri-articular injection Arthroplasty Replacement Knee Retrospective Studies business.industry Blood loss Retrospective cohort study medicine.disease Thrombosis Antifibrinolytic Agents Pulmonary embolism medicine.anatomical_structure RC925-935 Total knee arthroplasty Anesthesia Orthopedic surgery Administration Intravenous Complication business Research Article medicine.drug |
Zdroj: | BMC Musculoskeletal Disorders BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-4 (2021) |
ISSN: | 1471-2474 |
DOI: | 10.1186/s12891-021-04591-0 |
Popis: | Background The administration of an intra-articular injection (IAI) of tranexamic acid (TXA) has been demonstrated to be effective in reducing both blood loss and transfusion rate during total knee arthroplasty (TKA); however, few studies have reported the efficiency of a peri-articular injection (PAI) of TXA. We studied the efficiency of a PAI of TXA in reducing blood loss during TKA. Methods Fifty patients undergoing primary simultaneous bilateral TKA were enrolled in this retrospective study. The right knee received a PAI of 1 g of TXA (Group I), and the left knee received an IAI of 1 g of TXA (Group II). The clinical outcome measures were a change in blood loss from Hemovac drains and surgical time. Results The decrease in blood loss from the Hemovac was significantly lower in Group I (460.1 ± 36.79 vs. 576.0 ± 34.01, P Conclusions A PAI of TXA may reduce blood loss more efficiently than an IAI of TXA during TKA without increased complications such as surgical site infection, poor wound healing, skin necrosis, pulmonary embolism, and deep vein thrombosis. |
Databáze: | OpenAIRE |
Externí odkaz: |