Intracoronary doppler guide wire versus stress single-photon emission computed tomographic thallium-201 imaging in assessment of intermediate coronary stenosis
| Autor: | David Lasorda, Tony Farah, Douglas S. Schulman, James D. Joye, Nathaniel Reicher, Bryan C. Donohue |
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| Rok vydání: | 1994 |
| Předmět: |
Male
medicine.medical_specialty chemistry.chemical_element Coronary Disease Constriction Pathologic Sensitivity and Specificity Constriction Coronary artery disease Coronary circulation Predictive Value of Tests Coronary Circulation Internal medicine medicine Humans Prospective Studies Ultrasonography Interventional Aged Tomography Emission-Computed Single-Photon business.industry Coronary flow reserve Heart Middle Aged medicine.disease Coronary Vessels Thallium Radioisotopes Stenosis medicine.anatomical_structure chemistry Exercise Test Cardiology Thallium Female Cardiology and Cardiovascular Medicine business Perfusion Blood Flow Velocity Artery |
| Zdroj: | Journal of the American College of Cardiology. 24:940-947 |
| ISSN: | 0735-1097 |
| DOI: | 10.1016/0735-1097(94)90853-2 |
| Popis: | Objectives. The purpose of this study was to compare measures of coronary flow reserve by an intracoronary Doppler guide wire with results of stress single-photon emission computed tomographic (SPECT) thallium-201 imaging in patients with intermediate coronary artery disease (40% to 70% stenosis). Background. Visual assessment of the coronary arteriogram as a means of predicting the physiologic significance of intermediate coronary stenoses is inaccurate. Coronary flow reserve is a reliable marker of the functional importance of a coronary lesion. The recent development of an intracoronary Doppler guide wire permits routine assessment of coronary flow reserve distal to coronary artery stenoses. Methods. We prospectively evaluated coronary flow reserve in 30 subjects with intermediate stenoses using an intracoronary Doppler guide wire during elective coronary angiography. Patients subsequently underwent stress SPECT thallium-201 testing, and the blinded interpretations were correlated. Coronary flow reserve in a control group with normal coronary arteries classified our sample into group 1 (abnormal flow reserve |
| Databáze: | OpenAIRE |
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