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Background: Pregnancy manifests number of change in the normal physiology. Important of these changes are those which alter the hematological parameters. Hematological profile is considered one of the factors affecting pregnancy and its outcome. Anemia is the most common hematological problem in pregnancy. Objective: To assess the hematological profile of pregnant women in comparison with non pregnant women (as a control). Methodology: Comparative cross sectional study was conducted from March to May, 2016, on 110 pregnant and 110 non pregnant women at Dilla University Referral Hospital. A structured, pretested and interviewer administered questionnaire and laboratory tests were used to obtain data. Data was analyzed using the statistical soft ware SPSS version 20. Logistic regression, independent t test and one way ANOVA was used. P value less than 0.05 were taken as statistical significant. Result: The result showed that pregnant women exhibited statistically significant decrease value of RBC, Hb, HCT, MCHC, Lymphocyte, MID and PLT counts when compared with non pregnant. White blood cell, neutrophils and MCH were significantly higher in pregnant women compared to non pregnant women. No significant difference in MCV and RDW of pregnant women compared to non pregnant women. There was a significant decrease in RBC, Hb and HCT in the 2nd trimester compared to 1st trimester pregnancy. The RDW value increased significantly in third trimester when compared with 1st trimester pregnancy. The prevalence of anemia obtained in this study was 15.5%. Pregnant women who had primary educational level were 6.28 times more likely to be anemic compared to higher educational level. Conclusion: There was a significant difference in the majority of hematological parameters between pregnant and non pregnant women. RBC, Hb, HCT, MCHC, Lymphocyte, MID and platelet counts were significantly decreased whereas WBC, neutrophils and MCH were significantly increased in pregnant women. Therefore, there is a need to monitor these parameters during pregnancy and thus improve the outcome of pregnancy. Key terms: Hematological profile, pregnant women, anemia |
