Platinum and zinc oxide modified carbon nitride electrode as non-enzymatic highly selective and reusable electrochemical diabetic sensor in human blood
| Autor: | Krishnamoorthy Vaishali, Habibulla Imran, Sindhuraj Antony Francy, Venkataraman Dharuman, Palinci Nagarajan Manikandan |
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| Rok vydání: | 2020 |
| Předmět: |
Blood Glucose
Materials science Inorganic chemistry Biophysics chemistry.chemical_element 02 engineering and technology Zinc Biosensing Techniques Nitride Electrochemistry 01 natural sciences chemistry.chemical_compound X-Ray Diffraction Limit of Detection Nitriles Diabetes Mellitus Humans Physical and Theoretical Chemistry Electrodes Platinum Detection limit Spectrum Analysis 010401 analytical chemistry Graphitic carbon nitride Reproducibility of Results General Medicine 021001 nanoscience & nanotechnology 0104 chemical sciences chemistry Linear range Electrode Zinc Oxide 0210 nano-technology Oxidation-Reduction |
| Zdroj: | Bioelectrochemistry (Amsterdam, Netherlands). 137 |
| ISSN: | 1878-562X |
| Popis: | Development of non-enzymatic glucose sensor is essential to reduce the cost of diabetes regular monitoring. Here, graphitic carbon nitride (g-C3N4) is modified with platinum and zinc oxide for non-enzymatic electrochemical glucose sensing in physiological conditions for the first time in the literature. The interactions between Pt, g-C3N4 and the ZnO are studied using different physicochemical characterization techniques. The Electrochemical glucose sensing at the ZnO-Pt-gC3N4 occurs at low applied potential of +0.20 V (vs. Ag/AgCl) with high sensitivity 3.34 μA/mM/cm2 and fast response (5 s) time. This sensor exhibited a wide linear range 0.25–110 mM with lower limit of detection of 0.1 µM. The architectured sensor was evaluated in human blood, serum and urine samples. The sensor is 4 time reusable in whole blood without activity deterioration. This reusable surface helps to reduce the cost of strip. |
| Databáze: | OpenAIRE |
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