Risk of major cardiovascular and cerebrovascular complications after elective surgery in patients with sleep-disordered breathing

Autor: Babak Mokhlesi, Colin Suen, Talha Mubashir, Frances Chung, Clodagh M. Ryan, Rabail Chaudhry, Jean Wong
Rok vydání: 2020
Předmět:
Zdroj: European Journal of Anaesthesiology. 37:688-695
ISSN: 1365-2346
0265-0215
DOI: 10.1097/eja.0000000000001267
Popis: BACKGROUND There is limited and conflicting data on whether sleep-disordered breathing (SDB) is associated with postoperative major cardiovascular and cerebrovascular events (MACCE), and mortality. OBJECTIVES To determine whether SDB is associated with increased risks of MACCE, mortality and length of hospital stay. DESIGN Retrospective cohort analysis from the Nationwide Inpatient Sample. SETTING Adults who underwent elective abdominal, orthopaedic, prostatic, gynaecological, thoracic, transplant, vascular or cardiac surgery in the United States of America between 2011 and 2014. PATIENTS The study cohort included 1813 974 surgical patients, of whom 185 615 (10.2%) had SDB. Emergency or urgent surgical procedures were excluded. MAIN OUTCOME MEASURES The incidences of MACCE, respiratory and vascular complications, in-hospital mortality and mean length of hospital stay were stratified by SDB. Linear and logistic regression models were constructed to determine the independent association between SDB and outcomes of interest. RESULTS The incidences of MACCE [25.3 vs. 19.8%, odds ratio (OR) 1.20, P
Databáze: OpenAIRE