Pulmonary Alveolar Microlithiasis and Rheumatoid Arthritis: A Case Report and Review of the Literature
| Autor: | Mohammed Mokhtar, Safwan Mohammed M. Alim, Omaima Badr, Ahmedhusam Alahmed, Abdullah Saad A. Alsharif, Kholoud Al-Maabdi, Mohammed Alahmadi, Waleed Hafiz, Rakan O Alotaibi |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
030203 arthritis & rheumatology
Pathology medicine.medical_specialty business.industry Case Report General Medicine Disease Diseases of the musculoskeletal system medicine.disease Asymptomatic 03 medical and health sciences 0302 clinical medicine 030228 respiratory system RC925-935 Slow progression Pulmonary alveolar microlithiasis Rheumatoid arthritis Parenchyma medicine medicine.symptom business Antirheumatic drugs Histological examination |
| Zdroj: | Case Reports in Rheumatology, Vol 2021 (2021) Case Reports in Rheumatology |
| ISSN: | 2090-6897 2090-6889 |
| Popis: | Pulmonary alveolar microlithiasis is a rare autosomal recessive condition that is characterized by the formation of excessive calcium phosphate microliths in the alveoli. Most patients are diagnosed in adulthood due to the slow progression of the disease. Children with this disease are asymptomatic, and changes in the lung parenchyma are usually discovered incidentally. The diagnosis is made by the combination of a positive chest imaging and histological examination. Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by chronic seropositive symmetrical inflammatory polyarthritis with numerous extra-articular manifestations. It targets the lining of the synovial membranes, frequently affects females more than males, and is treated with the disease-modifying antirheumatic drugs (DMARDs). If left untreated, it leads to increased morbidity, mortality, and socioeconomic burdens. In this case, we report a 19-year-old young man who presented with clinical and radiographic features of PAM associated with RA. |
| Databáze: | OpenAIRE |
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