The Economic and societal burden of multiple sclerosis on lebanese society: a cost-of-illness and quality of life study protocol
Autor: | Silvia M. A. A. Evers, Mickaël Hiligsmann, Ingrid E. H. Kremer, Caroline Daccache, Hala Darwish, Rana Rizk, Samia J. Khoury, Jalal Dahham |
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Přispěvatelé: | RS: CAPHRI - R2 - Creating Value-Based Health Care, Health Services Research |
Rok vydání: | 2021 |
Předmět: |
Gerontology
UNMET NEEDS TRIBUNE Multiple Sclerosis IMPACT TREATMENT EXPERIENCE Context (language use) Quality of life Cost of Illness Health care Cost of illness Medicine Humans Pharmacology (medical) Lebanon utilities health care economics and organizations Retrospective Studies Estimation Protocol (science) Health economics business.industry Health Policy Multiple sclerosis Cost-of-illness EQ-5D General Medicine MS Health Care Costs medicine.disease humanities PREVALENCE INSIGHTS Cross-Sectional Studies Caregivers economic burden Quality of Life business study protocol |
Zdroj: | Expert Review of Pharmacoeconomics & Outcomes Research, 22(5), 869-876. Routledge/Taylor & Francis Group |
ISSN: | 1744-8379 1473-7167 |
Popis: | This protocol describes the estimation of the societal costs and quality-of-life (QOL) burden of multiple sclerosis (MS) in Lebanon. This cross-sectional, prevalence-based burden-of-illness study was carried out in a premier MS center in Lebanon. We enrolled Lebanese patients aged 18 years and older who had been diagnosed with MS more than 6 months. The study uses a bottom-up approach to estimate the cost-of-illness (COI) and QOL using a retrospective face-to-face interview questionnaire. This resource utilization questionnaire was adapted to the Lebanese context by clinical and health economics experts. The methodologies used to estimate the consumption of healthcare resources, informal care, and productivity losses are well-defined and aligned with the Lebanese healthcare system. Costs are presented overall and by MS severity levels. QOL is measured using the EuroQOL (EQ-5D-5 L) and Multiple Sclerosis International Quality of Life (MusiQoL) instrument. This protocol pioneers in informing the design of future COI and QOL studies in low - and middle-income countries (LMICs), as the methods used could be applied in similar LMICs. Furthermore, we provide recommendations and discuss the challenges of conducting a high-quality burden-of-illness study in LMICs and the steps taken to meet them, using the case of Lebanon. |
Databáze: | OpenAIRE |
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