MR spectroscopy findings in tuberculous spondylitis; comparison with Modic type-I end-plate changes and metastatic vertebral disease
| Autor: | Levent Buluç, Ercüment Çiftçi, Ali Demirci, Ahmet Ilgazli, Ihsan Anik, Gür Akansel, Hasan Tahsin Sarisoy, Yonca Anik |
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| Rok vydání: | 2009 |
| Předmět: |
Male
In vivo magnetic resonance spectroscopy Magnetic Resonance Spectroscopy Sensitivity and Specificity Lesion Statistical significance medicine Water index Humans Tuberculosis Radiology Nuclear Medicine and imaging Spondylitis Spinal Neoplasms medicine.diagnostic_test business.industry Reproducibility of Results Water Magnetic resonance imaging General Medicine medicine.disease Lipids Vertebra medicine.anatomical_structure cardiovascular system Female Protons Normal vertebrae medicine.symptom Nuclear medicine business Biomarkers Intervertebral Disc Displacement |
| Zdroj: | European Journal of Radiology. 71:324-332 |
| ISSN: | 0720-048X |
| DOI: | 10.1016/j.ejrad.2008.05.002 |
| Popis: | Purpose To define single-voxel proton magnetic resonance spectroscopy (MRS) findings of vertebral tuberculous spondylitis (TBS), Modic type-I end-plate changes (MTEC) and metastatic vertebral disease (MVD). Materials and methods Fifteen patients with TBS, 15 with MTEC and 15 with MVD were included. MRS from the diseased vertebral body as well as normal vertebral body was examined. Water and lipid peak were measured, water-to-lipid ratio (WLR) and for each patient lesion water index (LWI, the ratio of WLRs from diseased to normal vertebrae) were calculated. Results The mean WLR of normal and pathologic vertebra was 0.91 and 7.13 in TBS group, 0.84 and 3.49 in MTEC group and 0.65 and 3.17 in MVD group, respectively. The mean LWI was 10.68 in TBS, 6.04 in MTEC and 6.42 MVD groups. Statistical significance was not achieved between the WLR and LWI of the TBS, MTEC nor MVD group ( p > 0.05). Conclusion The mean values of WLR and LWI in the TBS group are relatively higher than MTEC and MVD groups, with the difference being statistically insignificant. |
| Databáze: | OpenAIRE |
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