St. Jude Medical Trifecta aortic valve: results from a prospective regional multicentre registry
| Autor: | Andrea Blasio, Giordano Tasca, Samuele Bichi, Luigi Martinelli, Andrea Biondi, Cristian Leva, Giovanni Mariscalco, Germano Di Credico, Paolo Vanelli, Fabrizio Corti, Lorenzo Menicanti, Amando Gamba, Ottavio Alfieri, Giampiero Esposito, Cesare Beghi, Silvia Mariani, Giovanni Paolini, Benedetta De Chiara, R. Gherli, Claudio Russo, Paolo Borsani, Carlo Antona |
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| Přispěvatelé: | Mariscalco, G, Mariani, S, Bichi, S, Biondi, A, Blasio, A, Borsani, P, Corti, F, De Chiara, B, Gherli, R, Leva, C, Russo, Cf, Tasca, G, Vanelli, P, Alfieri, Ottavio, Antona, C, Di Credico, G, Esposito, G, Gamba, A, Martinelli, L, Menicanti, L, Paolini, G, Beghi, C., Russo, C, Alfieri, O, Beghi, C |
| Jazyk: | angličtina |
| Předmět: |
Pulmonary and Respiratory Medicine
Aortic valve Adult Male medicine.medical_specialty Time Factors medicine.medical_treatment Aortic Valve Insufficiency Heart valve bioprosthesis Prosthesis Design Biomaterials Valve replacement Aortic valve replacement Internal medicine medicine 80 and over Endocarditis Humans Heart valve Prospective Studies Heart valve replacement Aged Aged 80 and over Bioprosthesis business.industry Aortic valve replacement Biomaterials Heart valve bioprosthesis Heart valve replacement Adult Aged Aged 80 and over Aortic Valve Stenosis General Medicine Aortic Valve Stenosis Middle Aged medicine.disease Surgery Cardiac surgery medicine.anatomical_structure Cardiothoracic surgery Aortic valve stenosis Aortic Valve Heart Valve Prosthesis Cardiology Female Follow-Up Studies Cardiology and Cardiovascular Medicine business Research Article |
| Zdroj: | Journal of Cardiothoracic Surgery |
| ISSN: | 1749-8090 |
| DOI: | 10.1186/s13019-015-0379-6 |
| Popis: | Background: The Trifecta aortic bioprosthesis (St. Jude Medical, Inc., St. Paul, MN, USA) is a stented pericardial heart valve with excellent preliminary results. Aim of the study was to evaluate its early clinical and hemodynamic performances in a multicenter regional registry. Methods: Between January 2011 and June 2012, 178 consecutive patients undergoing aortic valve replacement with the Trifecta bioprosthesis were prospectively enrolled at 9 Italian centers. Clinical and echocardiographic data were collectedat discharge, 6-months and at 1-year postoperatively. Results: The average age was 75.4 +/- 7.7 years, and 95 (53 %) were men. Indication for valve replacement included stenosis in 123 patients (69 %), mixed lesions in 25 (14 %), and regurgitation in 30 (17 %). Ninety-three (52 %) patients were in NYHA functional class III/IV. Hospital mortality accounted for 5 (2.8 %) patients. No valve-related perioperative complications were encountered. Median follow-up was 20.5 months (range: 1-34). Early (6 months) thromboembolic events and two endocarditis (1 explant) were registered. No valve thrombosis or structural deterioration were observed after discharge. At 30-months, freedom from all-cause mortality was 87 %, freedom from valve-related mortality 99.4 %, freedom from endocarditis 97.5 %, and freedom from valve explants 98 %. At 1-year, mean gradients ranged from 8 to 16 mmHg, and effective orifice area indexes from 1.0 to 1.2 cm(2)/m(2) for valve sizes from 19 to 27 mm, respectively. No patients had severe prosthesis-patient mismatch. Conclusions: Trifecta bioprosthesis provided favourable clinical and hemodynamic results over time. |
| Databáze: | OpenAIRE |
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