In-depth analysis of local recurrence of giant cell tumour of bone with soft tissue extension after intralesional curettage
| Autor: | Wei-Bin Zhang, Ming-Jue Si, Xiao-Yi Ding, Yong Lu, Lianjun Du, Chengs-Sheng Wang, Liang Chen |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.medical_treatment Bone Neoplasms Soft Tissue Neoplasms Curettage Young Adult medicine Humans Neoplasm Invasiveness Radiology Nuclear Medicine and imaging Giant Cell Tumor of Bone medicine.diagnostic_test business.industry Ultrasound Intralesional curettage Soft tissue Interventional radiology Magnetic resonance imaging General Medicine Middle Aged Surgical procedures Surgery Giant cell Female Neoplasm Recurrence Local business |
| Zdroj: | La radiologia medica. 119:861-870 |
| ISSN: | 1826-6983 0033-8362 |
| DOI: | 10.1007/s11547-014-0396-x |
| Popis: | The aim of this study was to assess the local recurrence rate of giant cell tumour of bone (GCTB) with soft tissue extension, to identify characteristics of the soft tissue extension that can best indicate recurrence of GCTB after intralesional curettage.A total of 48 cases of GCTB with soft tissue extension after intralesional curettage were recruited. Patients were divided into two groups based on various objective features of soft tissue extension including size, number, margins, involvement of adjacent tissues, signal intensity, static enhancement and Jaffe grade. The local recurrence rate was compared using the Chi-square test and Chi-square value correction for continuity. Risk factors were assessed by multivariate logistic regression analysis.The local recurrence rate was significantly different according to soft tissue extension size, number and margins (p0.05). There was no significant difference in the groups of adjacent tissue involvement and Jaffe grade (p0.05). Size, number and margins of the soft tissue extension were independent risk factors of local recurrence of GCTB after intralesional curettage (p0.05).The local recurrence rate of GCTB with soft tissue extension after intralesional curettage is higher if the soft tissue extension is large, multiple and lacking bone envelope integrity. For cases with the above-mentioned features, we suggest that the higher recurrence rate can be taken into full consideration when choosing appropriate surgical procedures. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink