Supplementary Figures S1 - S4 from Genome-Wide Gene Expression Changes in the Normal-Appearing Airway during the Evolution of Smoking-Associated Lung Adenocarcinoma

Autor: Humam Kadara, Avrum E. Spira, Junya Fujimoto, Paul Scheet, Ignacio I. Wistuba, Arafat Tfayli, Hassan Chami, Nadine Darwiche, Georges Nemer, Junya Fukuoka, Sayuri Nunomura-Nakamura, Wenhua Lang, Smruthy Sivakumar, Tina L. McDowell, Li Xu, Ansam Sinjab, Jacob Kantrowitz
Rok vydání: 2023
DOI: 10.1158/1940-6207.22533308
Popis: S1. Lung tumor development in NNK-exposed Gprc5a-/- mice. S2. Evolutionarily conserved patterns of tobacco-carcinogen mediated gene expression in murine and human airway epithelia. S3. Early and persistent changes in mouse airway gene expression in vivo following tobacco carcinogen exposure and during lung oncogenesis. S4. Gene profiles downregulated in the mouse normal-appearing airway field of injury are overall suppressed in lung tumors relative to adjacent normal lung.
Databáze: OpenAIRE