Update of the CLRP TG-43 parameter database for low-energy brachytherapy sources
Autor: | Marc J. P. Chamberland, Christian Harry Allen, David W. O. Rogers, Rowan M. Thomson, Randle E. P. Taylor, Martin P. Martinov, Habib Safigholi |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Computer science
medicine.medical_treatment Brachytherapy FOS: Physical sciences computer.software_genre Imaging phantom 030218 nuclear medicine & medical imaging Set (abstract data type) 03 medical and health sciences 0302 clinical medicine Low energy medicine Dosimetry Radiation treatment planning Radiometry Database Radiotherapy Planning Computer-Assisted Radiotherapy Dosage General Medicine Physics - Medical Physics Radiation therapy 030220 oncology & carcinogenesis Medical Physics (physics.med-ph) Laboratories computer Monte Carlo Method |
Popis: | PURPOSE: To update the Carleton Laboratory for Radiotherapy Physics (CLRP) TG-43 dosimetry database for low-energy (< 50 keV) photon-emitting low-dose rate (LDR) brachytherapy sources utilizing the open-source EGSnrc application egs_brachy rather than the BrachyDose application used previously for 27 LDR sources in the 2008 CLRP version (CLRPv1). CLRPv2 covers 40 sources (Pd-103, I-125, Cs-131). A comprehensive set of TG-43 parameters is calculated, including dose-rate constants, radial dose functions with functional fitting parameters, 1D and 2D anisotropy functions, along-away dose-rate tables, Primary-Scatter separation dose tables (for some sources), and mean photon energies. The database also documents the source models which will become part of the egs_brachy distribution. METHODS: Datasets are calculated after a systematic recoding of the source geometries using the egs++ geometry package and its egs_brachy extensions. Full scatter water phantoms with varying voxel resolutions in cylindrical coordinates are used for dose calculations. New statistical uncertainties of source volume corrections for phantom voxels which overlap with brachytherapy sources are implemented in egs_brachy, and all CLRPv2 data include these uncertainties. For validation, data are compared to CLRPv1 and other data in the literature. DATA ACCESS/FORMAT: Data are available at https://physics.carleton.ca/ clrp/egs_brachy/seed_database_v2. As well as being presented graphically in comparisons to previous calculations, data are available in Excel (.xlsx) spreadsheets for each source. APPLICATIONS: The database has applications in research, dosimetry, and brachytherapy planning. This comprehensive update provides the medical physics community with more accurate TG-43 dose evaluation parameters, as well as fully-benchmarked source models distributed with egs_brachy. 29 pages, 8 figures, 2 tables |
Databáze: | OpenAIRE |
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