Pulmonary pleomorphic carcinoma with pseudoprogression during nivolumab therapy and the usefulness of tumor markers: A case report
Autor: | Akihiro Yoshimura, Yoji Urata, Taisuke Tsuji, Shinsuke Shiotsu, Tatsuya Yuba, Chieko Takumi, Ryosuke Hamashima, Noriya Hiraoka |
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Rok vydání: | 2018 |
Předmět: |
nivolumab
pulmonary pleomorphic carcinoma business.industry Pleural effusion Immune checkpoint inhibitors immune checkpoint inhibitor pseudoprogression Case Report Case Reports General Medicine Pleomorphic carcinoma medicine.disease 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Cytokeratin 19 fragment tumor marker Cancer research Pulmonary metastasis Medicine 030212 general & internal medicine Nivolumab business Pseudoprogression Tumor marker |
Zdroj: | Clinical Case Reports |
ISSN: | 2050-0904 |
DOI: | 10.1002/ccr3.1627 |
Popis: | Key Clinical Message Pseudoprogression was reported as one of the unconventional responses during immune checkpoint inhibitor therapy. A 70‐year‐old man with pulmonary pleomorphic carcinoma received nivolumab therapy. Pleural effusion and pulmonary metastasis increased, however then shrank and serum cytokeratin 19 fragment levels decreased. Serum tumor marker might help to distinguish pseudoprogression. |
Databáze: | OpenAIRE |
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