A Sweet Diagnosis for a Non-Resolving Rash
Autor: | Kshitij Thakur, Arezoo Ghaneie, Edward F Chan, Kah Poh Loh, Jian Liang Tan |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
medicine.drug_class Antibiotics Dermatology Malaise 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine azacitidine-associated sweet’s syndrome Erythematous plaque medicine Internal Medicine sweet’s syndrome Sweet's syndrome business.industry General Engineering medicine.disease Rash subcutaneous sweet’s syndrome myelodysplastic syndrome SSS Oncology 030220 oncology & carcinogenesis Corticosteroid medicine.symptom Panniculitis business neutrophilic panniculitis |
Zdroj: | Cureus |
ISSN: | 2168-8184 |
Popis: | Subcutaneous Sweet's syndrome (SSS) is a rare variant of Sweet's syndrome (SS), clinically characterized by erythematous plaques or nodules with a histologic pattern demonstrating a neutrophilic panniculitis (NP). We report a case of a 74-year-old woman with myelodysplastic syndrome (MDS) who presented with persistent fever, malaise, and non-resolving generalized erythematous nodules and was found to have an MDS-related SSS. SSS should be entertained and other causes of NP should be excluded prior to treating a patient with systemic corticosteroids. Early diagnosis of SSS in a patient not responding to broad-spectrum antibiotics is crucial as it helps to minimize unnecessary prolonged antibiotics exposure in this era of antimicrobial resistance. In patients with frequent relapses, a slow corticosteroid taper could be beneficial. |
Databáze: | OpenAIRE |
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