| Autor: |
F, Bandino, R, Thota, A L, Pendolino, K, Chaidas, S, Jeyaretna, T, Lawrence, P, Martinez-Devesa, A, Qureishi |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Rhinology journal. |
| ISSN: |
0300-0729 |
| DOI: |
10.4193/rhin22.070 |
| Popis: |
Background: Rhinosinusitis-induced brain abscesses are rare but can result in devastating long-term sequalae and mortality; they require a high index of suspicion with early imaging to start early empiric parenteral antibiotic treatment covering aerobes and anaerobes. Methodology: Our study was a retrospective analysis on 32 patients who were treated at Oxford University Hospitals for rhinosinusitis-induced brain abscess between February 2013 and June 2020. Results: Mean age of presentation was 45.83 for adults and 11.14 for children. Subdural collection was the most frequent abscess but 25% of patients had multiple sites of collection; the majority were in the frontal lobe. The most commonly identified pathogens were Streptococcus milleri group and Staphylococcus aureus; 93.75% of the patients were treated with combined Ceftriaxone and Metronidazole for an average of 8 weeks. Conclusions: In our series most patients received also a prompt and aggressive surgical treatment with combined neurosurgical and ENT procedures in the majority; this was especially important in case of subdural empyema, Streptococcus milleri infection and direct intracranial spread of infection. More than half of the patients were treated with a single surgical procedure. Despite aggressive treatment, one third of patients experienced long-term neurological sequelae; there were no deaths. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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