Dipolar pathways in multi-spin and multi-dimensional dipolar EPR spectroscopy

Autor:	Luis Fábregas-Ibáñez, Valerie Mertens, Irina Ritsch, Tona von Hagens, Stefan Stoll, Gunnar Jeschke
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Macromolecular Substances Electron Spin Resonance Spectroscopy Proteins General Physics and Astronomy Spin Labels Physical and Theoretical Chemistry
Zdroj:	Physical Chemistry Chemical Physics, 24 (37)
ISSN:	1463-9084 1463-9076
Popis:	Dipolar electron paramagnetic resonance (EPR) experiments, such as double electron-electron resonance (DEER), measure distributions of nanometer-scale distances between unpaired electrons, which provide valuable information for structural characterization of proteins and other macromolecular systems. We present an extension to our previously published general model based on dipolar pathways valid for multi-dimensional dipolar EPR experiments with more than two spin-1/2 labels. We examine the 4-pulse DEER and TRIER experiments in terms of dipolar pathways and show experimental results confirming the theoretical predictions. This extension to the dipolar pathways model allows the analysis of previously challenging datasets and the extraction of multivariate distance distributions. Physical Chemistry Chemical Physics, 24 (37) ISSN:1463-9084 ISSN:1463-9076
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238022124d66a9c78442c02944e470d9 https://hdl.handle.net/20.500.11850/572244 Zobrazit plný text záznamu