Primary retroperitoneal germ cell tumours: Excision via a thoracoabdominal extraperitoneal approach
| Autor: | Gordon J. S. Rustin, M. J. Seckl, Timothy J. Christmas, A. P. Doherty, E. S. Newlands |
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| Rok vydání: | 1997 |
| Předmět: |
Adult
Male medicine.medical_specialty Chorionic gonadotrophin medicine.medical_treatment Chorionic Gonadotropin Disease-Free Survival Antineoplastic Combined Chemotherapy Protocols Biomarkers Tumor medicine Humans Retroperitoneal Neoplasms Survival rate Chemotherapy business.industry Extraperitoneal approach Middle Aged Abdominal mass Surgery Treatment Outcome medicine.anatomical_structure Germinoma alpha-Fetoproteins Anterior approach medicine.symptom Ultrasonography Tomography X-Ray Computed business Germ cell Follow-Up Studies |
| Zdroj: | British Journal of Surgery. 84:1022-1025 |
| ISSN: | 1365-2168 0007-1323 |
| DOI: | 10.1002/bjs.1800840736 |
| Popis: | Background Primary retroperitoneal germ cell tumours usually present as a large abdominal mass in young men. The testes are normal on examination and ultrasonography but there are usually raised serum levels of human chorionic gonadotrophin and/or a-fetoprotein. Methods Fourteen men (median age 33 years) with primary retroperitoneal germ cell tumours were treated by chemotherapy followed by surgical resection of the primary tumour and metastases via a thoracoabdominal extraperitoneal approach. Results There was minimal morbidity. The survival rate was 13 of 14 and the disease-free survival rate was 11 of 14 after a median follow-up of 15 months. Conclusion The thoracoabdominal extraperitoneal approach for the removal of retroperitoneal germ cell tumours and their metastases after chemotherapy improves tumour clearance, morbidity and recovery time compared with the transperitoneal anterior approach. |
| Databáze: | OpenAIRE |
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