Viral hepatitis C and organ transplantation
| Autor: | Libuše Husová, Vladimír Mejzlík |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Liver Cirrhosis Male medicine.medical_specialty Cirrhosis Sustained Virologic Response medicine.medical_treatment 030204 cardiovascular system & hematology Liver transplantation Antiviral Agents Gastroenterology Organ transplantation Young Adult 03 medical and health sciences 0302 clinical medicine Pharmacotherapy Interferon Internal medicine Internal Medicine Humans Medicine 030212 general & internal medicine Aged business.industry Hepatitis C Hepatitis C Chronic Middle Aged medicine.disease Liver Transplantation Transplantation surgical procedures operative Drug Therapy Combination Female Cardiology and Cardiovascular Medicine business Viral hepatitis medicine.drug |
| Zdroj: | Vnitřní lékařství. 63:531-534 |
| ISSN: | 1801-7592 0042-773X |
| Popis: | At the Centre for Cardiovascular and Transplantation Surgery, Brno (CKTCH), a total of 638 liver transplantations were performed from the beginning of the transplantation programme on 2/2 1983 to 1/1 2017. Of the overall number of 638 transplantations indicated based on cirrhosis with chronic hepatitis C (HCV), 68 patients (11 %) underwent liver transplantation. Patients with HCV diagnosis were treated both while on the waiting list and after liver transplantation (LT). There was interferon as well as interferon-free therapy used during the treatment. 15 patients received interferon therapy after LT with only 2 of them achieving a sustained virological response 2/15 (13 %). 28 patients received interferon-free therapy after LT. A sustained virological response (SVR 12) was reached by 26/28 (93 %) patients.Key words: liver transplantation - viral hepatitis C. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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