Color and pulsed Doppler sonography, gray-scale imaging, and serum CA 125 in the assessment of adnexal disease
| Autor: | Mladen Predanic, Fatma A. Aleem, Nikos Vlahos, Mamdouh Moukhtar, Joseph A. Pennisi |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Adnexal lesions Sensitivity and Specificity Adnexal mass Predictive Value of Tests Preoperative Care Medicine Humans Ultrasonography Doppler Color Aged Pulsed doppler business.industry Medical screening Obstetrics and Gynecology Reproducibility of Results Middle Aged medicine.disease Predictive value Adnexal tumors Adnexal Diseases ROC Curve Ultrasonography Doppler Pulsed CA-125 Antigen Ultrasound imaging Female Radiology business |
| Zdroj: | Obstetrics and gynecology. 88(2) |
| ISSN: | 0029-7844 |
| Popis: | Objective To compare color and pulsed Doppler sonography with gray-scale ultrasound imaging and serum CA 125 levels in establishing accurate preoperative diagnoses of adnexal masses. Methods Medical records of 109 patients referred with preexisting adnexal lesions were reviewed retrospectively by comparing preoperative ultrasonic data (gray-scale imaging and color and pulsed Doppler findings) with serum CA 125 levels. Results Eighty-three masses were removed surgically, confirming seven malignancies and 76 benign tumors, and 26 masses were followed; 15 regressed and 11 persisted. Color and pulsed Doppler sonography showed the highest sensitivity, followed by gray-scale imaging, whereas serum CA 125 levels revealed the highest specificity in distinguishing malignant from benign adnexal tumors. All three methods had high negative predictive values (96–100%), whereas only serum CA 125 had a positive predictive value greater than 50%. Conclusion Color and pulsed Doppler sonography, which demonstrate a tumor angiogenic activity, are as accurate as gray-scale imaging in the assessment of adnexal lesions. Together with serum CA 125 marker levels, they produce high negative predictive values, providing reassurance that an adnexal mass is benign. |
| Databáze: | OpenAIRE |
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