Salivary rheumatoid factor in primary and secondary Sjögren’s syndrome
| Autor: | Jesús Israel Rodríguez-Pulido, Andrea Alcázar-Pizaña, Norma Idalia Rodríguez-Franco, María Gabriela Chapa-Arizpe, Gloria Martínez-Sandoval, Janett Riega-Torres, Silvia Arely Triana-Reyes |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Autoimmune disease
Saliva medicine.medical_specialty saliva business.industry immunoglobulins Arthritis RK1-715 medicine.disease Gastroenterology rheumatoid factor sjogren's syndrome Internal medicine Dentistry Rheumatoid factor Medicine Secondary Sjögren's syndrome Xerophthalmia enzyme-linked immunosorbent assay Elisa method business General Dentistry Rheumatism |
| Zdroj: | Journal of Oral Research, Vol 8, Iss 3, Pp 196-200 (2019) |
| ISSN: | 0719-2479 0719-2460 |
| Popis: | Sjögren's syndrome is a chronic autoimmune disease, characterized by the presence of hyposalivation and xerophthalmia, which in addition to other factors is diagnosed by the presence of rheumatoid factor in blood. The objective of the present study is to evaluate the presence of rheumatoid factor (IgG-IgM) in the saliva of patients with primary and secondary Sjögren's syndrome. Materials and methods: Forty samples from patients with primary and secondary Sjögren's syndrome previously diagnosed by the Arthritis and Rheumatism Specialist Center of the Autonomous University of Nuevo Leon were analyzed. Samples were taken from the saliva using the Carlson-Crittenden device to evaluate the IgG-IgM immunocomplex using the ELISA method. Results: No significant difference was found between the presence of IgM in primary (0.099±0.016) and secondary Sjögren syndrome (0.098±0.017), however, a high presence of IgG was found in the group of patients with secondary Sjögren's syndrome (0.134±0.054). Conclusion: The search for diagnostic tools using salivary biomarkers has come with economic and clinical advantages, however, in the present study no significant changes were found in salivary rheumatoid factor between both groups. |
| Databáze: | OpenAIRE |
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