An ecotoxicological characterization of nanocrystalline cellulose (NCC)
| Autor: | Pierre H. Martel, Christian Blaise, Brian I. O'Connor, Lauren Hall, Valerie Naish, Vance L. Trudeau, François Gagné, Tibor Kovacs |
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| Rok vydání: | 2010 |
| Předmět: |
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Canada Materials science Biomedical Engineering Cyprinidae Industrial Waste Toxicology medicine.disease_cause Ecotoxicology Risk Assessment Aquatic species chemistry.chemical_compound Environmental risk parasitic diseases medicine Animals Food science Cellulose Zebrafish Low toxicity urogenital system business.industry Mutagenicity Tests Reproduction Biotechnology Nanostructures chemistry Daphnia Methyl cellulose Carboxymethylcellulose Sodium Oncorhynchus mykiss embryonic structures Toxicity Hepatocytes Female business Genotoxicity Water Pollutants Chemical |
| Zdroj: | Nanotoxicology. 4(3) |
| ISSN: | 1743-5404 |
| Popis: | The pulp and paper industry in Canada is developing technology for the production and use of nanocrystalline cellulose (NCC). A key component of the developmental work is an assessment of potential environmental risks. Towards this goal, NCC samples as well as carboxyl methyl cellulose (CMC), a surrogate of the parent cellulosic material, were subjected to an ecotoxicological evaluation. This involved toxicity tests with rainbow trout hepatocytes and nine aquatic species. The hepatocytes were most sensitive (EC20s between 10 and 200 mg/l) to NCC, although neither NCC nor CMC caused genotoxicity. In tests with the nine species, NCC affected the reproduction of the fathead minnow at (IC25) 0.29 g/l, but no other effects on endpoints such as survival and growth occurred in the other species at concentrations below 1 g/l, which was comparable to CMC. Based on this ecotoxicological characterization, NCC was found to have low toxicity potential and environmental risk. |
| Databáze: | OpenAIRE |
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