Myocardial Infarction without Coronary Occlusion
| Autor: | Bengt Gerdin, B. Nyström, Gunnar Helmius |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Erythrocyte Aggregation
Male medicine.medical_specialty Hot Temperature Phosphorylases Platelet Aggregation Myocardial Infarction Erythrocyte aggregation Coronary circulation Left coronary artery Coronary Circulation Internal medicine medicine.artery medicine Animals Myocardial infarction Microscopy Sheep business.industry Myocardium Electrocardiography in myocardial infarction General Medicine Blood flow medicine.disease Disease Models Animal medicine.anatomical_structure Coronary occlusion Cardiology Female business Artery |
| Zdroj: | Upsala Journal of Medical Sciences. 87:67-80 |
| ISSN: | 2000-1967 0300-9734 |
| DOI: | 10.3109/03009738209178410 |
| Popis: | The macroscopic, histologic and enzyme-histochemical characteristics of the myocardial lesion obtained after heating of a thermoprobe in a branch of the left coronary artery in sheep is reported. In 13 sheep such myocardial lesions were produced distal to the location of the thermoprobe. Alterations were observed in accordance with generally accepted morphologic criteria for myocardial infarction. The coronary artery branch in which the thermoprobe was located showed erythrocyte and platelet aggregates immediately after the heating episode, which disappeared within a few min, as demonstrated by coronary arteriography. Injection of radiolabelled microspheres into the coronary circulation after induction of the myocardial lesion, cryosectioning of the heart and autoradiography revealed a lack of blood flow in the damaged myocardial region. We consider this new method a suitable tool for further studies on the complex pathology involved in the development of myocardial infarction. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|