A case of infective endocarditis associated with atopic dermatitis perioperatively treated with dupilumab

Autor:	Yukihiko Tomita, Mika Nakanishi, Toshihiro Imanishi, Takeshi Kato, Eri Oota
Rok vydání:	2019
Předmět:	030203 arthritis & rheumatology Adult Male Mitral regurgitation medicine.medical_specialty Endocarditis business.industry Antibodies Monoclonal Dermatology Case presentation Atopic dermatitis medicine.disease Antibodies Monoclonal Humanized Dupilumab Cardiac surgery Dermatitis Atopic 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Cerebral embolism Infective endocarditis Internal medicine medicine Humans business
Zdroj:	The Journal of dermatological treatment. 30(7)
ISSN:	1471-1753
Popis:	Background: Several case reports and reviews support a relationship between atopic dermatitis (AD) and infective endocarditis (IE). Here, we present a case of severe AD suspected of causing IE. Case presentation: A 21-year-old man with severe AD was admitted to our hospital due to unidentified fever, syncope, and headache. He was diagnosed with IE with cerebral embolism and mitral regurgitation. Before elective cardiac surgery, he was subcutaneously administered dupilumab for 2 months to control AD. Dupilumab improved AD, and cardiac surgery was performed without complications. Conclusions: Dupilumab may be effective in AD cases as preparation for cardiac surgery.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225914cdb5fb8a245dcaae277f9ccf37 https://pubmed.ncbi.nlm.nih.gov/30628496 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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