The Canadian Forces Cancer and Mortality Study II: a longitudinal record-linkage study protocol
| Autor: | David Boulos, Mark A. Zamorski, Linda VanTil, Richard Trudeau, Elizabeth Rolland-Harris, Murray Weeks, Kristen Simkus, Alexander Reicker, Huda Masoud |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
business.industry Research Military service Incidence (epidemiology) Cancer Retrospective cohort study General Medicine medicine.disease 01 natural sciences Cancer registry 010104 statistics & probability 03 medical and health sciences 0302 clinical medicine Health promotion 030220 oncology & carcinogenesis Family medicine Cohort Medicine 0101 mathematics Record Linkage Study business |
| Zdroj: | CMAJ Open. 6:E619-E627 |
| ISSN: | 2291-0026 |
| DOI: | 10.9778/cmajo.20170125 |
| Popis: | Background Military service exposes personnel to unusual situations with unclear health-related implications, and to identify both immediate and delayed risks, part of health surveillance includes examination of mortality and cancer rates that extends beyond periods of military service. The main aim of the Canadian Forces Cancer and Mortality Study II (CFCAMS II) is to describe the mortality and cancer experience of Canadian Armed Forces personnel (serving and released; about 230 000 people), with the further aim of informing health promotion and prevention programs for serving personnel and services for veterans after they leave the military. Methods This protocol is for a retrospective cohort study of serving and released Canadian Armed Forces personnel who enrolled on or after Jan. 1, 1976 in the Regular Force or Class C of the Reserve Force. To create our cohort, we identified record-linkage methods as the most appropriate mechanism to study mortality and cancer in those with a history of Canadian military service. Statistics Canada will link the CFCAMS II cohort file to the Canadian Vital Statistics (Mortality) and Canadian Cancer Registry databases for outcomes up to Dec. 31, 2014. The linkage will be stored in their highly secure linkage environment. Statistical analyses will be broadly divided into mortality and cancer incidence. Results We will quantify mortality and cancer morbidity incidence and survival using multiple established methods, as well as age-period-cohort regression models to describe the relation between military service and mortality and cancer outcomes. Interpretation The findings will represent novel and sound evidence on the risks and protective factors of military life. |
| Databáze: | OpenAIRE |
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