The association between cone density and visual function in the macula of patients with retinitis pigmentosa
| Autor: | Tomoko Ueda-Consolvo, Hironori Ozaki, Atsushi Hayashi, Toshihiko Oiwake, Tomoko Nakamura |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Visual acuity genetic structures Fundus Oculi Visual Acuity Cellular and Molecular Neuroscience Young Adult Optical coherence tomography Foveal Ophthalmology Retinitis pigmentosa medicine Humans In patient Macula Lutea Fluorescein Angiography Retrospective Studies medicine.diagnostic_test business.industry Middle Aged medicine.disease eye diseases Sensory Systems Foveal sensitivity Ophthalmoscopy Cone (topology) Visual function Retinal Cone Photoreceptor Cells Female sense organs medicine.symptom business Retinitis Pigmentosa Tomography Optical Coherence Follow-Up Studies |
| Zdroj: | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 257(9) |
| ISSN: | 1435-702X |
| Popis: | We observed cone photoreceptors by using adaptive optics (AO) fundus camera and optical coherence tomography (OCT) in patients with retinitis pigmentosa (RP) and examined the correlations between cone photoreceptors and visual function over 2 years. Six patients with RP were studied. All patients underwent measurement using best-corrected decimal visual acuity, OCT, a Humphrey Field Analyzer with the 10-2 test grid pattern, and AO. AO images of the foveal center were obtained using an rtx1™ AO fundus camera, and cone counting was performed at 0.5 mm from the foveal center. AO detected a decrease of cone density over 2 years in RP patients. However, visual acuity, foveal sensitivity, and photoreceptor thickness were not changed over the 2 years. AO images showed a decrease in the number of foveal cone densities over 2 years in patients with RP. AO may shorten the period required to predict the RP progression rate. |
| Databáze: | OpenAIRE |
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