Vitamin D levels were significantly higher during and after lifestyle intervention in pregnancy: A randomized controlled trial
| Autor: | Marianne Andersen, Dorte Møller Jensen, Jan Stener Jørgensen, Mette Tanvig, Christina Anne Vinter, Per Ovesen |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
obesity medicine.medical_specialty Diet Reducing Denmark vitamin D MASS vitamin D deficiency law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Pregnancy law Lifestyle intervention medicine Vitamin D and neurology Humans Obesity 030212 general & internal medicine Life Style POPULATION RISK 030219 obstetrics & reproductive medicine Obstetrics business.industry Obstetrics and Gynecology Gestational age lifestyle intervention General Medicine Vitamin D Deficiency obese women POSTPARTUM medicine.disease Intervention studies Pregnancy Complications Pregnancy Trimester First Treatment Outcome PHYSICAL-ACTIVITY Dietary Supplements randomized controlled trial Female pregnancy WEIGHT business |
| Zdroj: | Tanvig, M H, Jensen, D M, Andersen, M S, Ovesen, P G, Jorgensen, J S & Vinter, C A 2020, ' Vitamin D levels were significantly higher during and after lifestyle intervention in pregnancy : A randomized controlled trial ', Acta Obstetricia et Gynecologica Scandinavica, vol. 99, no. 3, pp. 350-356 . https://doi.org/10.1111/aogs.13722 Tanvig, M H, Jensen, D M, Andersen, M S, Ovesen, P G, Jørgensen, J S & Vinter, C A 2020, ' Vitamin D levels were significantly higher during and after lifestyle intervention in pregnancy : A randomized controlled trial ', Acta Obstetricia et Gynecologica Scandinavica, vol. 99, no. 3, pp. 350-356 . https://doi.org/10.1111/aogs.13722 |
| ISSN: | 1600-0412 0001-6349 |
| DOI: | 10.1111/aogs.13722 |
| Popis: | INTRODUCTION: Vitamin D deficiency is common in pregnancy, especially in obese women. Lifestyle intervention could potentially result in higher levels of vitamin D. We therefore aimed to study the effect of lifestyle intervention during pregnancy on serum levels of 25-hydroxyvitamin D (25(OH)D).MATERIAL AND METHODS: A total of 360 obese women were randomized before gestational age 14 weeks to lifestyle intervention (diet and exercise) or routine clinical follow up (controls). Clinical outcomes and levels of 25(OH)D were determined three times: At gestational age 12-15 weeks (baseline), gestational age 28-30 weeks and 6 months postpartum.RESULTS: A total of 304 (84%) women completed the intervention study and 238 (66%) attended postpartum follow up. Vitamin D levels were similar in the two groups at baseline. At gestational age 28-30 weeks and 6 months postpartum, 25(OH)D levels were significantly higher in the intervention group than in controls (75.6 vs 66.8 nmol/L, P = 0.009) and (54.8 vs 43.1 nmol/L, P = 0.013), respectively. Concurrently, vitamin D deficiency (25-hydroxyvitamin D CONCLUSIONS: Lifestyle intervention during pregnancy was associated with significantly increased vitamin D levels in late pregnancy and postpartum compared with controls. |
| Databáze: | OpenAIRE |
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