Synaptic activity controls autophagic vacuole motility and function in dendrites

Autor:	Sandra Maday, Maria C. Vogel, Jessica Brandt Herr, Anip Anand, Christina Miranda, Vineet Vinay Kulkarni
Rok vydání:	2021
Předmět:	Cell signaling Motility Hippocampus Vacuole Hippocampal formation Biology Rats Sprague-Dawley Synapse Mice Cell Movement Autophagy medicine Animals Spotlight Axon Neurons Autophagosomes Dendrites Cell Biology Axons Rats Cell biology medicine.anatomical_structure Synapses Vacuoles Lysosomes
Zdroj:	The Journal of Cell Biology
ISSN:	1540-8140 0021-9525
DOI:	10.1083/jcb.202002084
Popis:	Guimas Almeida previews new work from the Maday laboratory demonstrating the regulation of autophagosome dynamics and function within dendrites by synaptic activity. Regulation of autophagy in neurons remains unclear. In this issue, Kulkarni et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202002084) show with elegant live imaging that in dendrites, but not in axons, autophagosome motility and function is regulated by synaptic activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2131ffaab5f792b8200e20f228b0aa34 https://doi.org/10.1083/jcb.202002084 Zobrazit plný text záznamu