Epstein-Barr virus NK and T cell lymphoproliferative disease: report of a 2018 international meeting
| Autor: | Leticia Quintanilla-Martinez, Irini Manoli, Young-Hyeh Ko, Hiroshi Kimura, Keiji Iwatsuki, Elaine S. Jaffe, Stefania Pittaluga, Koichi Ohshima, Jeffrey I. Cohen |
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| Rok vydání: | 2019 |
| Předmět: |
Epstein-Barr Virus Infections
Herpesvirus 4 Human Cancer Research Asia T-Lymphocytes T cell medicine.disease_cause Article Virus 03 medical and health sciences 0302 clinical medicine Aggressive NK-cell leukemia hemic and lymphatic diseases medicine Humans T-cell lymphoma B cell business.industry Hematology medicine.disease Epstein–Barr virus Lymphoproliferative Disorders Lymphoma Europe Killer Cells Natural medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Immunology business Diffuse large B-cell lymphoma 030215 immunology |
| Zdroj: | Leuk Lymphoma |
| ISSN: | 1029-2403 1042-8194 |
| Popis: | Epstein-Barr virus (EBV) normally infects B cells, but in some persons the virus infects T or NK cells. Infection of B cells can result in infectious mononucleosis, and the virus is associated with several B cell malignancies including Hodgkin lymphoma, Burkitt lymphoma, and diffuse large B cell lymphoma. Infection of T or NK cells with EBV is associated with extranodal NK/T cell lymphoma, aggressive NK-cell leukemia, systemic EBV-associated T-cell lymphoma, and chronic active EBV disease, which in some cases can include hydroa vacciniforme-like lymphoproliferative disease and severe mosquito bite allergy. While NK and T cell lymphoproliferative disease is more common in Asia and Latin America, increasing numbers of cases are being reported from the United States and Europe. This review focuses on classification, clinical findings, pathogenesis, and recent genetic advances in NK and T cell lymphoproliferative diseases associated with EBV. |
| Databáze: | OpenAIRE |
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