Electrical Remodeling Following Percutaneous Pulmonary Valve Implantation
| Autor: | Carla M. Plymen, Fiona Walker, Aidan P Bolger, Philipp Lurz, Pier D. Lambiase, Andrew M. Taylor, Johannes Nordmeyer, Seamus Cullen, Louise Coats, Twin Yen Lee, Philipp Bonhoeffer, Alamgir Kabir, John Deanfield |
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| Rok vydání: | 2011 |
| Předmět: |
Male
medicine.medical_specialty Heart disease Heart Valve Diseases Sudden cardiac death Electrocardiography Young Adult QRS complex Heart Conduction System Heart Rate Pulmonary Valve Replacement Internal medicine Humans Medicine Prospective Studies cardiovascular diseases Tetralogy Pulmonary Valve medicine.diagnostic_test business.industry Arrhythmias Cardiac Prognosis medicine.disease medicine.anatomical_structure Heart Valve Prosthesis Pulmonary valve cardiovascular system Cardiology Female Electrical conduction system of the heart Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | The American Journal of Cardiology. 107:309-314 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/j.amjcard.2010.09.017 |
| Popis: | Sudden cardiac death in congenital heart disease is related to increased right ventricular end-diastolic volume (RVEDV), abnormalities of QRS duration, and QRS, JT, and QT dispersions. Surgical pulmonary valve replacement and percutaneous pulmonary valve implantation (PPVI) decrease RVEDV, but the effects of PPVI on surface electrocardiographic parameters are unknown. PPVI represents a pure model of RV mechanical and electrophysiologic changes after replacement. This prospective study sought to determine the effects of PPVI on surface electrocardiographic parameters: Ninety-nine PPVI procedures in patients with congenital heart disease (23.1 ± 10 years of age) were studied before, after, and 1 year after PPVI with serial electrocardiograms and echocardiogram/magnetic resonance images. Forty-three percent had pulmonary stenosis, 27% pulmonary regurgitation (PR), and 29% mixed lesions. In those with predominantly PR (n = 26), QRS duration decreased significantly (135 ± 27 to 128 ± 29 ms, p = 0.007). However, in the total cohort no significant change in QRS duration at 1 year was observed (137 ± 29 to 134 ± 29 ms). Corrected QT interval and QRS, QT, and JT dispersions significantly decreased at 1 year (p ≤0.001). RVEDV correlated with preprocedure QRS duration (r = 0.34, p |
| Databáze: | OpenAIRE |
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