Enrichment, in vitro and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
| Autor: | Tasnuva Sarwar Tunna, Md. Zaidul Islam Sarker, Kashif Ghafoor, Sahena Ferdosh, Juliana Md Jaffri, Fahad Y Al-Juhaimi, Md. Eaqub Ali, Md. Jahurul Haque Akanda, Md Shihabul Awal, Qamar Uddin Ahmed, Jinap Selamat |
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| Rok vydání: | 2017 |
| Předmět: |
0404 agricultural biotechnology
Process Chemistry and Technology General Chemical Engineering 010401 analytical chemistry Filtration and Separation 02 engineering and technology General Chemistry 04 agricultural and veterinary sciences 021001 nanoscience & nanotechnology 0210 nano-technology 040401 food science 01 natural sciences 0104 chemical sciences |
| DOI: | 10.6084/m9.figshare.5439772.v1 |
| Popis: | Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were analyzed pharmacologically, qualitatively and quantitatively to ascertain enrichment level. All three (3) antidiabetic compounds were effectively enriched at optimized conditions of temperature 60oC, pressure 40 MPa, co-solvent ratio 30% and CO2 flow rate of 5 ml min−1. SFE was found to be the better method for enrichment of the antidiabetic compounds than the CO2-Soxhlet method. Extraction conditions were seen to affect enrichment of desired compounds. |
| Databáze: | OpenAIRE |
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