Congenital lung malformations: Unresolved issues and unanswered questions
| Autor: | Silvia Montella, Francesca Santamaria, Francesco Raimondi, Marco Poeta, Melissa Borrelli, Francesco Borgia, Federica Annunziata, Andrew Bush |
|---|---|
| Přispěvatelé: | Annunziata, F., Bush, A., Borgia, E., Raimondi, F., Montella, S., Poeta, M., Borrelli, M., Santamaria, F. |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Family therapy
medicine.medical_specialty FETAL BRONCHOSCOPY Lung malformation Congenital cystic adenomatoid malformation Pulmonary sequestration CYSTIC ADENOMATOID MALFORMATION Prenatal diagnosis Review 030204 cardiovascular system & hematology SEQUESTRATION Multidisciplinary team Asymptomatic Pediatrics BRONCHIOLOALVEOLAR CARCINOMA 03 medical and health sciences 0302 clinical medicine 030225 pediatrics THORACOSCOPIC SEGMENTECTOMY HYDROPS-FETALIS medicine PRENATAL-DIAGNOSIS Intensive care medicine BRONCHIAL ATRESIA Children Lung Science & Technology Perioperative management Bronchogenic cyst business.industry Postnatal management lcsh:RJ1-570 lung malformations lcsh:Pediatrics Antenatal ultrasound medicine.disease medicine.anatomical_structure Pediatrics Perinatology and Child Health PULMONARY AIRWAY MALFORMATIONS Surgery medicine.symptom business Life Sciences & Biomedicine |
| Zdroj: | Frontiers in Pediatrics Frontiers in Pediatrics, Vol 7 (2019) |
| Popis: | Advances in prenatal and postnatal diagnosis, perioperative management, and postoperative care have dramatically increased the number of scientific reports on congenital thoracic malformations (CTM). Nearly all CTM are detected prior to birth, generally by antenatal ultrasound. After delivery, most infants do well and remain asymptomatic for a long time. However, complications may occur beyond infancy, including in adolescence and adulthood. Prenatal diagnosis is sometimes missed and detection may occur later, either by chance or because of unexplained recurrent or persistent respiratory symptoms or signs, with difficult implications for family counseling and substantial delay in surgical planning. Although landmark studies have been published, postnatal management of asymptomatic children is still controversial and needs a resolution. Our aim is to provide a focused overview on a number of unresolved issues arising from the lack of an evidence-based consensus on the management of patients with CTM. We summarized findings from current literature, with a particular emphasis on the vigorous controversies on the type and timing of diagnostic procedures, treatments and the still obscure relationship between CTM and malignancies, a matter of great concern for both families and physicians. We also present an algorithm for the assessment and follow-up of CTM detected either in the antenatal or postnatal period. A standardized approach across Europe, based on a multidisciplinary team, is urgently needed for achieving an evidence-based management protocol for CTM. |
| Databáze: | OpenAIRE |
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