miRNA-Dependent Activation of mRNA Translation

Autor: Xiao-Min Leng, Wen-Juan Ni
Rok vydání: 2016
Předmět:
Zdroj: MicroRNA. 5:83-86
ISSN: 2211-5366
DOI: 10.2174/2211536605666160825151201
Popis: MicroRNAs (miRNAs) are small and important RNA molecules. They can regulate gene expression at different levels. Although their biogenesis has been well documented, elucidation of miRNA-dependent activation of mRNA translation has just begun. Here, we highlighted different patterns of miRNA-dependent activation of mRNA translation: miRNA can activate mRNA translation through binding different target sites; in different sub-cellular locations; under different cellular circumstances. MiRNA-dependent activation of mRNA translation suggests unexpected functions of miRNA, that could provide new clues in functional studies of other ncRNAs.
Databáze: OpenAIRE